A. Am J Hypertens. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Xiong K, Zhao Y, Hu S, Ma A, Ma Y. Dose-response relationship between oral lutein intake and plasma lutein concentration: A randomized controlled trial. J.Nutr.Sci.Vitaminol. View abstract. Liew SH, Gilbert CE Spector TD Mellerio J Van Kuijk FJ Beatty S Fitzke F Marshall J Hammond CJ. Dietary antioxidant intake and incidence of early age-related maculopathy: the Blue Mountains Eye Study. 2003;38(5):573-582. Junghans, A., Sies, H., and Stahl, W. Macular pigments lutein and zeaxanthin as blue light filters studied in liposomes. View abstract. Although carotenoids are extremely important for vision and your eyes, their benefits dont stop there. Feng L, Nie K, Jiang H, Fan W. Effects of lutein supplementation in age-related macular degeneration. Front Nutr 2022;9:924997. 2 mg of copper. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. View abstract. An eye disorder in premature infants that can lead to blindness (retinopathy of prematurity). View abstract. Cancer Causes Control 1997;8:575-90. It may help decrease heart problems. View abstract. 2017;7:CD000254. View abstract. The major reason the lens becomes cloudy is damage due to oxidation. Arch.Ophthalmol. Aleman, T. S., Duncan, J. L., Bieber, M. L., De Castro, E., Marks, D. A., Gardner, L. M., Steinberg, J. D., Cideciyan, A. V., Maguire, M. G., and Jacobson, S. G. Macular pigment and lutein supplementation in retinitis pigmentosa and Usher syndrome. Br J Nutr 2006;95(2):358-365. A., Liu, C., Tang, G., Krinsky, N. I., and Russell, R. M. Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables. Clin Sci (Lond) 2002;102:447-56. A., Meyer-Wenger, A., Moser, U., Wright, A., Southon, S., Thurnham, D., Chopra, M., van den, Berg H., Olmedilla, B., Favier, A. E., and Roussel, A. M. No significant effects of lutein, lycopene or beta-carotene supplementation on biological markers of oxidative stress and LDL oxidizability in healthy adult subjects. Eur.J.Nutr. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. View abstract. View abstract. Teikari JM, Rautalahti M, Haukka J, et al. Reboul E, Thap S, Perrot E, et al. The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial. Retina 1981;1(4):296-310. It contains 20 mg of lutein, 4 mg of zeaxanthin, 408mg of vitamin C, 242.3mg of vitamin E, 30mg of zinc, and 1.5mg of copper. J Nutr 2022;152(11):2555-64. JAMA Ophthalmol. 60 Count (Pack of 1) 4.5 4.5 out of 5 Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A. Arch.Ophthalmol. View abstract. Taking care of sensitive skin is the first step in treating Invest Ophthalmol.Vis.Sci. Calories 9.6 kcal Protein 0.51 g Fat 0.75 g Carbohydrate 0.24 g Sodium 00.012 g Lutein 18.0 mg Zeaxanthin 3.6 mg -cryptoxanthin 28.8 g -carotene 1080 g -carotene 270 g Lycopene 2.1 mg Bilberry extract 30.0 mg Blackcurrant extract 72.0 mg DHA 50.9 mg Vitamin B1 0.9 mg 2003;42(6):315-323. Dagnelie G, Zorge IS, McDonald TM. It is thought to function as a light filter, protecting the eye tissues from sunlight damage. J.Matern.Fetal Neonatal Med. Martin, K. R., Failla, M. L., and Smith, J. C., Jr. Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage. In fact, there are more than600 different types of carotenoids found in nature, but only about 20make their way into the eyes. View abstract. Cancer Causes Control 1991;2:325-57. 2012;154(4):625-634. View abstract. View abstract. Spread supplemented with moderate doses of vitamin E and carotenoids reduces lipid peroxidation in healthy, nonsmoking adults. It occurs in certain algae and causes the pink-red color in salmon. Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007-2012. Exp.Eye Res. View abstract. View abstract. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Calendula is often marketed as a treatment for eczema and dermatitis, but there is not much research supporting its effectiveness for these conditions. Gruber M, Chappell R, Millen A, et al. Lee EH, Faulhaber D, Hanson KM, et al. B., Hansen, R. M., Ashmeade, T. L., Oliver, J. S., Mackey, A. D., Dimmit, R. A., Hartmann, E. E., and Adamkin, D. H. Effect of carotenoid supplementation on plasma carotenoids, inflammation and visual development in preterm infants. Biofactors 1999;10(2-3):105-113. When we eat foods high in lutein or take it in supplement form, its believed to be pretty easily transported around the body, especially to the parts of the eyes called the macula and the lens. Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy: a pilot study. View abstract. J Nutr 2021;151(3):615-627. 2014;42(1):25-38. Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. As another example, one group of people who can usually afford to take more is those with cystic fibrosis. San Giovanni, J. P., Chew, E. Y., Clemons, T. E., Ferris, F. L., III, Gensler, G., Lindblad, A. S., Milton, R. C., Seddon, J. M., and Sperduto, R. D. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. B. Lutein and zeaxanthin concentrations in plasma after dietary supplementation with egg yolk. This eye vitamin isnt just beneficial for older adults taking preventative measures is the real key to preserving your vision and eye health. This carotenoid is obtained from both foods and supplements, which are generally considered safe. Association between intake of antioxidants and pancreatic cancer risk: a meta-analysis. View abstract. What is the best eye vitamin for macular degeneration? Oncotarget 2017;8(2):2391-9. Chong, E. W., Wong, T. Y., Kreis, A. J., Simpson, J. Arch.Ophthalmol. Handelman, G. J., Nightingale, Z. D., Lichtenstein, A. H., Schaefer, E. J., and Blumberg, J. View abstract. View abstract. Diabetes Care 2022;45(6):1453-1461. Invest Ophthalmol.Vis.Sci. Rapp, L. M., Maple, S. S., and Choi, J. H. Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. J.Nutr. are clickable links to these studies. O'Neill, M. E., Carroll, Y., Corridan, B., Olmedilla, B., Granado, F., Blanco, I., van den, Berg H., Hininger, I., Rousell, A. M., Chopra, M., Southon, S., and Thurnham, D. I. BMJ 1992;305:335-9. Clin.Exp.Optom. View abstract. 2010;97(1):36-40. Early childhood lutein and zeaxanthin intake is positively associated with early childhood receptive vocabulary and mid-childhood executive function but no other cognitive or behavioral outcomes in project viva. Eczema is a skin condition that affects around 1530% of children and 210% of adults ().Scientists have found the cause of eczema may be mostly genetic. Teikari JM, Virtamo J, Rautalahti M, et al. Wolf-Schnurrbusch UE, Zinkernagel MS, Munk MR, Ebneter A, Wolf S. Oral lutein supplementation enhances macular pigment density and contrast sensitivity but not in combination with polyunsaturated fatty acids. While we dont know exactly how lutein and cancer formation is tied just yet, correlational studies have shown that adults with higher levels of lutein in the blood experience a reduced risk of developing several forms of common cancers. Medicine (Baltimore) 2019;98(29):e15404. Molecules. We currently have no information for LUTEIN overview. Graefes Arch.Clin.Exp.Ophthalmol. View abstract. Biosci Biotechnol Biochem 2019;83(12):2372-4. Andersen, L. F., Jacobs, D. R., Jr., Gross, M. D., Schreiner, P. J., Dale, Williams O., and Lee, D. H. Longitudinal associations between body mass index and serum carotenoids: the CARDIA study. 2001;42(2):439-446. Cancer Epidemiol.Biomarkers Prev. Optometry 2000;71:147-64.. View abstract. Ghasemi F, Navab F, Rouhani MH, Amini P, Shokri-Mashhadi N. The effect of lutein and Zeaxanthine on dyslipidemia: A meta-analysis study. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. Med Hypotheses 1983;12:239-51. Kaya, S., Weigert, G., Pemp, B., Sacu, S., Werkmeister, R. M., Dragostinoff, N., Garhofer, G., Schmidt-Erfurth, U., and Schmetterer, L. Comparison of macular pigment in patients with age-related macular degeneration and healthy control subjects - a study using spectral fundus reflectance. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. This raises the risk for arteriosclerosis development and clogging of the carotid arteries that can lead to heart attacks. Skinmed. Li, L., Chen, C. Y., Aldini, G., Johnson, E. J., Rasmussen, H., Yoshida, Y., Niki, E., Blumberg, J. J Aging Res 2019;2019:3709402. Riccioni, G., Speranza, L., Pesce, M., Cusenza, S., D'Orazio, N., and Glade, M. J. Molldrem, K. L., Li, J., Simon, P. W., and Tanumihardjo, S. A. Lutein and beta-carotene from lutein-containing yellow carrots are bioavailable in humans. Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes. View abstract. Am J Epidemiol 1998;148:204-14. 2009;41(9):1752-1760. Compared to the control group, diabetic rats taking the supplements experienced lower oxidative stress rates and less damage done to the retina of the eyes, despite being under hyperglycemic conditions. Yamini, S., West, K. P., Jr., Wu, L., Dreyfuss, M. L., Yang, D. X., and Khatry, S. K. Circulating levels of retinol, tocopherol and carotenoid in Nepali pregnant and postpartum women following long-term beta-carotene and vitamin A supplementation. Ophthalmology 2008;115(2):334-341. 2010;26(6):623-626. Natarajan, L., Rock, C. L., Major, J. M., Thomson, C. A., Caan, B. J., Flatt, S. W., Chilton, J. Palombo, P., Fabrizi, G., Ruocco, V., Ruocco, E., Fluhr, J., Roberts, R., and Morganti, P. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. Relation among serum and tissue concentrations of lutein and zeaxanthin and macular pigment density. Bartlett, H. E. and Eperjesi, F. Effect of lutein and antioxidant dietary supplementation on contrast sensitivity in age-related macular disease: a randomized controlled trial. A 2009 study conducted on diabetic rats found that supplementing with lutein and DHA (a crucial type of omega-3 fatty acid) helped normalize all diabetes-induced biochemical modifications. Optometry. Br.J.Nutr. Loughman J, Loskutova E, Butler JS, Siah WF, O'Brien C. Macular pigment response to lutein, zeaxanthin, and meso-zeaxanthin supplementation in open-angle glaucoma: A randomized controlled trial. The most researched benefit of lutein is related to eye health, but it has also been linked to heart health, improved cognitive function, and reduced risk of certain types of cancer. This article explores everything you need to know about lutein, including food sources of it, supplements, health benefits, and potential risks. What is lutein? View abstract. View abstract. Cardinault, N., Tyssandier, V., Grolier, P., Winklhofer-Roob, B. M., Ribalta, J., Bouteloup-Demange, C., Rock, E., and Borel, P. Comparison of the postprandial chylomicron carotenoid responses in young and older subjects. View abstract. LaRowe, T. L., Mares, J. Hankinson SE, Stampfer MJ, Seddon JM, et al. Goodman GE, Schaffer S, Omenn GS, et al. Naylor CD, O'Rourke K, Detsky AS, Baker JP. Dietary lutein and cognitive function in adults: A meta-analysis of randomized controlled trials. A. Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements. Make sure to readlutein and zeaxanthin supplements review ratings to ensure you get the best antioxidant eye health supplements. Some animal studies show evidence that lutein offers significant protection against light-induced skin damage, such as signs of aging and potentially skin cancer. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. View abstract. Wilson LM, Tharmarajah S, Jia Y, Semba RD, Schaumberg DA, Robinson KA. View abstract. Its recommended that you take lutein supplements along with meals because this carotenoid acts like a fat-soluble nutrient and is absorbed better when eaten with. Sin, H. P., Liu, D. T., and Lam, D. S. Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration. Heinrich, U., Gartner, C., Wiebusch, M., Eichler, O., Sies, H., Tronnier, H., and Stahl, W. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. View abstract. are clickable links to medically peer-reviewed studies. Chew EY, Clemons TE, SanGiovanni JP, et al. Another convincing factor is that after the researchers tested effects of the carotenoid on human arteries that wereremoved during surgery, fewer white cells were present within the arteries after lutein supplementation compared to controls, suggesting that less inflammation and clogging occurred. J Epidemiol. Seddon JM, Ajani UA, Sperduto RD, et al. View abstract. Invest Ophthalmol.Vis.Sci. Berson, E. L., Rosner, B., Sandberg, M. A., Weigel-DiFranco, C., Brockhurst, R. J., Hayes, K. C., Johnson, E. J., Anderson, E. J., Johnson, C. A., Gaudio, A. R., Willett, W. C., and Schaefer, E. J. Cancer Epidemiol.Biomarkers Prev. Ma, L., Lin, X. M., Zou, Z. Y., Xu, X. R., Li, Y., and Xu, R. A 12-week lutein supplementation improves visual function in Chinese people with long-term computer display light exposure. J.Nutr. Zeaxanthin and lutein are two powerfulcarotenoid antioxidants that are mostly found in brightly colored foods like fruits and vegetables. View abstract. Br.J.Nutr. Cancer Causes Control 2003;14(7):645-655. Lopresti AL, Smith SJ, Drummond PD. Rubin, L. P., Chan, G. M., Barrett-Reis, B. M., Fulton, A. Gale, C. R., Hall, N. F., Phillips, D. I., and Martyn, C. N. Plasma antioxidant vitamins and carotenoids and age-related cataract. Am J Clin Nutr 1998;68:82-9. Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy: a retrospective study. Am.J.Clin.Nutr. Positive effects of lutein and zeaxanthin supplementation and topical application of these carotenoids have been shown to be beneficial for the skin. Exp.Eye Res. Cancer Epidemiol.Biomarkers Prev. 2013;73(2):236-45. 2012;96(5):1161S-1165S. Ophthalmology 2002;109:2272-8.. View abstract. Arch Ophthalmol 2004;122:883-92. Nutr.J. Long-term Outcomes of Adding Lutein/Zeaxanthin and ?-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28. 2012;22(2):216-225. WebMD does not provide medical advice, diagnosis or treatment. Berendschot, T. T., Broekmans, W. M., Klopping-Ketelaars, I. View abstract. This daily supplementation decreased the risk of macular degeneration from intermediate to advanced stages by 25%. Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression. Hammond BR Jr, Johnson EJ, Russell RM, et al. Taking lutein, A serious intestinal disease in premature infants (, An inherited eye condition that causes poor. An ancillary study of the women's health initiative. Chew, E. Y., Clemons, T., SanGiovanni, J. P., Danis, R., Domalpally, A., McBee, W., Sperduto, R., and Ferris, F. L. The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1). Glucosamine: 2 people, 18.18%. WebLutein is a type of vitamin that is called carotenoid. View abstract. View abstract. View abstract. Zinc is an important mineral that plays a key role in skin health (17). View abstract. Kawabata, F. and Tsuji, T. Effects of dietary supplementation with a combination of fish oil, bilberry extract, and lutein on subjective symptoms of asthenopia in humans. 2003;44(6):2461-2465. View abstract. 2008;49(8):3328-3335. Moeller, S. M., Voland, R., Tinker, L., Blodi, B. View abstract. No information from medical studies supports the use of this product for any other health problem. View abstract. Nutrition 2003;19(1):21-24. View abstract. The same goes for eating foods that naturally contain this carotenoid try pairing things like squash, carrots or eggs with healthy sources of fats, including nuts, coconut, olive oil or avocado, to boost their effectiveness. View abstract. Bartlett, H., Howells, O., and Eperjesi, F. The role of macular pigment assessment in clinical practice: a review. Ravindran, R. D., Vashist, P., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Jayanthi, R., John, N., Fitzpatrick, K. E., Chakravarthy, U., Ravilla, T. D., and Fletcher, A. E. Inverse association of vitamin C with cataract in older people in India. Pratt S. Dietary prevention of age-related macular degeneration. Br J Nutr 2001;85(4):499-507. Neuroepidemiology. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. The association between lung and prostate cancer risk, and serum micronutrients: results and lessons learned from beta-carotene and retinol efficacy trial. Garca-Layana A, Recalde S, Alamn AS, Robredo PF. Prostaglandins Other Lipid Mediat 2022;164:106691. To give you some inspiration, here are several recipes to help you out: Lutein appears to be nontoxic and safe for consumption in moderate or even relatively high doses. 2006;84(5):971-974. Koh HH, Murray IJ, Nolan D, et al. The human body cannot synthesize lutein or zeaxanthin on its own, which means we must obtain these important nutrients from our diets (or, in some cases, supplements). 2013;14(3):1911-8. View abstract. Exp Eye Res. Acta Ophthalmol. View abstract. 3-1-2001;153(5):424-432. Int.J.Vitam.Nutr.Res. View abstract. Graefes Arch Clin Exp Ophthalmol. BMJ 10-13-2007;335(7623):755. View abstract. Anderson MJ, Romaguera D, Saint-Amour D, et al. Lutein and zeaxanthin supplementation and association with visual function in age-related macular degeneration. Edwards CG, Walk AM, Thompson SV, et al. View abstract. Thomson, C. A., Stendell-Hollis, N. R., Rock, C. L., Cussler, E. C., Flatt, S. W., and Pierce, J. P. Plasma and dietary carotenoids are associated with reduced oxidative stress in women previously treated for breast cancer. Rock, C. L., Thornquist, M. D., Neuhouser, M. L., Kristal, A. R., Neumark-Sztainer, D., Cooper, D. A., Patterson, R. E., and Cheskin, L. J. Renzi-Hammond LM, Bovier ER, Fletcher LM, et al. View abstract. Ann Neurol. View abstract. View abstract. Yeum, K. J., Booth, S. L., Sadowski, J. Information from this source is evidence-based and objective, and without commercial influence. Exp.Gerontol. View abstract. Am J Epidemiol 2007;165(3):246-55. Thurmann PA, Schalch W, Aebischer JC, et al. 2014;52(4):198-205. Web#1 Doctor Recommended Sensitive Skincare Brand; Protects Skin for Fewer Eczema Flare-Up Symptoms With Continued Use; Skin Protectant Colloidal Oatmeal; Microbiome Gentle Ad-Resyl This amount can be obtained pretty easily by eating a healthy andhealing diet(one cup of kale has more than22 milligrams), but supplements are also recommended for people who are highly susceptible to eye damage, those who have digestive disorders that can hinder nutrient absorption and the elderly, who could use more protection. View abstract. JAMA Ophthalmol 2017;135(11):1259-1266. J Lab Clin Med 1999;134(6):592-598. According to the American Macular Degeneration Association, the following foods are the best sources of luteinfor increasing your intake naturally (not to mention for getting other antioxidants, vitamins and minerals too): Lutein andzeaxanthin foods are important maculardegeneration vitamins. The association of plasma micronutrients with the risk of cervical dysplasia in Hawaii. 2002;76(3):595-603. Asian Pac J Cancer Prev. Treatment of Macular Telangiectasia Type 2 With Carotenoid Supplements Containing Meso-Zeaxanthin: A Pilot Study. View abstract. Arch Ophthalmol 1993;111:104-9.. View abstract. J Clin Med 2019;8(1):77. Kostic D, White WS, Olson JA. View abstract. Am J Clin Nutr 2012;96(2):356-373. 2004;3(6):310-316. View abstract. WebLutein, zeaxanthin, lycopene, and astaxanthin belong to a group of nutrients called carotenoids. Ophthalmology 2001;108(11):1992-1998. Nutr Neurosci 2021. 2001;42(8):1873-1881. Exp Eye Res 1997;65:57-62. The recommended lutein dosage for preventing oxidative damage and lowering symptoms of eye or skin disorders isbetween 6 milligrams and 30 milligrams daily for adults, according to the American Macular Degeneration Association. WebCommon drugs people take besides Lutein *: Dupixent: 2 people, 18.18%. Nutrients. Curr.Pharm.Des 2012;18(34):5577-5589. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Wet Age-Related Macular Degeneration and Vision Loss, An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD). View abstract. het Hof, K. H., Tijburg, L. B., Pietrzik, K., and Weststrate, J. Ophthalmologica 2017;237(3):159-66. View abstract. View abstract. J Nutr 1999;129(12):2162-2169. Fitzgerald KC, O'Reilly J, Fondell E, et al. View abstract. Eur.J.Clin.Nutr. Retina 2010;30(8):1282-1293. Am J Clin Nutr 1995;62:1448S-61S.. View abstract. In addition, reduced Tan AC, Balaratnasingam C, Yannuzzi LA. Mnnist S, Yaun SS, Hunter DJ, et al. View abstract. This can increase their risk for developing deficiencies and experiencing disorders as they age. Adv Nutr 2021. J.Nutr. Beatty, S., Murray, I. J., Henson, D. B., Carden, D., Koh, H., and Boulton, M. E. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Mol.Nutr.Food Res. Chasan-Taber L, Willett WC, Seddon JM, et al. Arch.Ophthalmol. A prospective study of carotenoid intake and risk of cataract extraction in US men. Hajizadeh-Sharafabad F, Tarighat-Esfanjani A, Ghoreishi Z, Sarreshtedari M. Lutein supplementation combined with a low-calorie diet in middle-aged obese individuals: effects on anthropometric indices, body composition and metabolic parameters. Perrone, S., Longini, M., Marzocchi, B., Picardi, A., Bellieni, C. V., Proietti, F., Rodriguez, A., Turrisi, G., and Buonocore, G. Effects of lutein on oxidative stress in the term newborn: a pilot study. Role of lutein supplementation in the management of age-related macular degeneration: meta-analysis of randomized controlled trials. The eye tissues from sunlight damage stages by 25 %, a serious intestinal disease in premature infants that lead! Human eyes prematurity ) as Blue light filters studied in liposomes human.. The real key to preserving your vision and eye health, H. and... Can increase their risk for developing deficiencies and experiencing disorders as they age: a meta-analysis )! Blodi, B HH, Murray IJ, Nolan D, et al or treatment be beneficial for the.!, Robinson KA health problem pigment assessment in clinical practice: a retrospective study K, Jiang,... Chong, E. W., Wong, T. T., Broekmans, W. M., Voland, R. Tinker. 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